Document Type : Research Paper

 Full Text


Department of Genetics, Faculty of Science, Nazarbayev University, Astana, Kazakhstan

Received: 05 October 2020                      Accepted: 23 November 2020                      Published: 01 December 2020

 10.22034/MBT.2020.120961                                                      XML Files


Today, the biggest limitation in gene therapy is the lack of appropriate vectors for gene transfer to cells and this causes dullness Process of Clinical treatments in this method. According to what was said, research on Making Vector systems is necessary. In developing different methods of gene therapy for human, choosing a safe and controllable vector with high performance to deliver the therapeutic gene to target cells, is the most key step of the process of designing and carrying out gene therapy. With the advances in nanotechnology and Nano-hydrogels, a new window of the knowledge of gene therapy is opened. The small size of Nano-hydrogels, have create new research opportunities for researchers specially in gene-therapy field and it have been promising in the treatment of many diseases, especially cancer and genetic disorders. However, to prove successful results of the investigation, more clinical trials are needed. Researches are so wide in the field of using Nano-hydrogels in Biomedical and Provide a comprehensive picture of this research is not an easy task. In this research have been tried to deal with the major research areas in the field of Nano-hydrogels used in gene therapy, as much as possible. Investigations showed that in the gene therapy, Nano-hydrogels as Non-viral vectors don’t have many of   Viral vectors problems.