Document Type : Original Article

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Department of Ophthalmology, Faculty of Medicine, Infectious Ophthalmic Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Received: 11 September 2021                   Accepted: 03 October 2021                Published: 06 December 2021

 10.22034/MBT.2021.315102.1006                                                       XML Files


Introduction: Keratoconus (KC) is the most common corneal ectatic disorder with a prevalence of about 1 in 2,000 people. KC is a progressive, non-inflammatory, almost bilateral and asymmetric of corneal. Corneal collagen cross-linking (CXL) with riboflavin and ultraviolet- A (UVA) is a new technique of mechanical stability of the cornea and prevention of keratoconus progression.
Purpose: Determining the relationship between changes in corneal density before and after collagen cross-linking surgery in patients with keratoconus
Materials and Methods This prospective study was performed on 45 eyes of 23 patients with keratoconus undergoing corneal collagen cross-linking treatment at Imam Khomeini Hospital in Ahvaz in 2019. Corneal densitometry (CD) and pachymetry were measured using Pentacam before CXL and at 3, 6 and 12 months after CXL. Also, all of the patients were evaluated in terms of best corrected visual acuity (BCVA), during follow-up.
Results: In this study, 23 people including 12 men (54.2%) and 11 women (45.8%) with a mean age of 25.2 ± 4.64 years in the age range of 18-34 years participated. The mean value of corneal density in total layer over the annular diameters 0-2 mm was 19.10±5.58, 22.31±5.64, 24.28±6.37 and 20.89±5.73 for before, 3 months, 6 months and 12 months after CXL, respectively (P = 0.001).